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But during treatment, if the toxins build up in the body faster than the liver can process them, hepatotoxicity may occur [139]

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2 The main sources of cellular ROS are mitochondria and nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, and peroxisomes containing xanthine oxidase and the inducible form of nitric oxide synthase, which produce superoxide anion and nitric oxide, respectively

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Some other adverse effects, such as hyponatremia, bleeding, and sexual dysfunction, are more prominent with either SNRIs or SSRIs (Wang et al., 2018)